question
Alice Ball
answer
black woman who found cure for hansens disease (leprosy) caused by mycobacterium leprae
normal treatment chaulmoogra oil
normal treatment chaulmoogra oil
question
sulfanilamides
answer
1935
protosil- dye, effective against Streptococcus. (cleaved to sulfanilamide in body)
sulfadrugs do same thing
protosil- dye, effective against Streptococcus. (cleaved to sulfanilamide in body)
sulfadrugs do same thing
question
Bactrim
answer
sulfadrug that treats UTI's, ear infection, respiratory
question
How sulfanilamides work
answer
Humans don't produce folic acid, injest it.
Bacteria need to produce it themselves.
Sulfanilamide formed inside of bacteria prevents synthesis of folic acid through competitive inhibition
Bacteria need to produce it themselves.
Sulfanilamide formed inside of bacteria prevents synthesis of folic acid through competitive inhibition
question
structure of Folic Acid
answer
P-PABA-G
pteridine- para amino benzoic acid- glutamic acid
pteridine- para amino benzoic acid- glutamic acid
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