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Toxins allow
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virulence
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Virulence
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microbes ability to infect or damage host
"virulence factor"
"virulence factor"
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Toxinosis
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diseased caused by bacterial toxin
NOT bacterial infection
NOT bacterial infection
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In toxinosis bacteria are
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dead
already produce toxin
already produce toxin
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2 types of toxinosis
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1. Exotoxin
2. Endotoxin
2. Endotoxin
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Exotoxin
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Go though transcription and translation first
secreted by a living bacteria
proteins
secreted by a living bacteria
proteins
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Types of Exotoxin
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1. Enterotoxin
2. Neurotoxin
2. Neurotoxin
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Who produced exotoxins
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specific species
ONLY virulent strains
ONLY virulent strains
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Where are exotoxin genes?
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found on plasmids
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Endotoxin
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ONLY G- bacteria
NOT secreted out
shed from G- outer membrane
NOT secreted out
shed from G- outer membrane
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BAD Endotoxins do NOT
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break down easily
lead to sever inflammation
lead to sever inflammation
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GOOD Endotoxins
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can correctly refine the immune system