question
Which of the following bacteria can cause life-threatening pseudomembranous colitis?
answer
Clostridium difficile
question
What is a key diagnostic indication of infection with Mycobacterium leprae?
answer
Loss of the sense of touch
question
Otitis media may lead to dangerous meningitis in children due to infection with _______________
answer
Streptococcus pneumoniae
question
Bacteria collected from a severely inflamed wound are sent to the lab for analysis. The results come back as follows: gram-positive cocci in irregular clusters, kinase and coagulase positive, and able to grow in the presence of most antibiotics except vancomycin. The bacteria in the wound are most likely _________________
answer
methicillin-resistant Staphylococcus aureus (MRSA)
question
The skin lesions characteristic of cutaneous infections with Bacillus anthracis are __________
answer
eschars
question
During a stay in the hospital, an accident victim develops symptoms of bacteremia. A blood sample shows the presence of gram-positive cocci in pairs. Lab tests determine that the bacteria are nonhemolytic and bile salt tolerant. The bacteremia is likely due to __________
answer
Enterococcus
question
What bacteria can cause pharygitis?
answer
Both Streptococcus equisimilus and S. pyogenes
question
Infections with Streptococcus pyogenes may progress to ____________, characterized by a skin rash that peels after about a week and a bright red swollen tongue.
answer
scarlatina
question
Anthrax, which means "charcoal" in Greek, derives its name from _______________________
answer
the black eschars it produces on human skin
question
Mycetoma, which is a painless long-lasting infection characterized by swelling, pus production, and draining sores, is caused by ____________
answer
Nocardia
question
A women comes to the emergency department with fever and vomiting. She soon develops a red rash all over her body, and her blood pressure begins to drop. What is one possible diagnosis?
answer
Toxic shock syndrome
question
The Quellung reaction is used to diagnose ____________________
answer
Streptococcus pneumoniae
question
How does the toxin from Clostridium tetani produce its action?
answer
The smaller polypeptide of its toxin can block the release of inhibitory neurotransmitters by inhibitory neurons in the CNS, causing simultaneous contraction of both muscles in an antagonistic pair
question
Over 90% of Staphylococcus aureus isolates penicillin-resistant. Why?
answer
They produce beta-lactamase
question
Increased sebum secretion can fuel overgrowth of the opportunistic pathogen ______________ in its normal habitat, leading to disease
answer
Propionibacterium acnes
question
How do group A streptococci camouflage themselves from white blood cells?
answer
They have hyaluronic acid capsules
question
What bacteria produce one of the most deadly toxins known?
answer
Clostridium botulinum
question
What statement about Bacilus anthracis is FALSE?
answer
It is primarily a disease of humans
question
What bacteria divide by "snapping division" in which daughter cells remain attached in characteristic V-shapes?
answer
Corynebacterium
question
What statement about "flesh-eating" streptococci is FALSE?
answer
It is considered a common complication of pyoderma
question
What is one virulence factor that differentiates Staphylococcus aureus from other species of staphylococci?
answer
It can produce coagulase
question
What has been historically classified as gram-negative bacteria but is genetically more similar to low G + C gram-positive bacteria?
answer
Mycoplasmas
question
What is NOT a feature of the pathogenesis of Clostridium perfringens?
answer
Inhibiting sensory neuron function
question
What disease is considered an autoimmune disease triggered by bacterial infection?
answer
Rheumatic feverr
question
Mycoplasma pneumoniae causes respiratory disease by _______________
answer
attaching to, inhibiting, and ultimately killing the ciliated epithelial cells of the trachea
question
Streptococcus pneumoniae is a leading cause of _______________
answer
otitis media
question
What is FALSE concerning tetanus?
answer
It's only source is from deep puncture wounds from rusty nails
question
The pus from an abscess in a patient's jaw contains microbes that form yellowish grainy masses and appear filamentous under the microscope. Neither antifungal medication nor a normal course of antibiotics has been effective in treating the infection. The abscess is likely the result of infection with _________________
answer
actinomyces
question
Streptococci are frequently classified by ________________
answer
lancefield antigen designations
question
What differentiates virulent strains of Streptococcus pneumoniae from nonvirulent strains?
answer
The presence of a polysaccharide capsule that protects it from digestion after endocytosis
question
Members of the genus Mycoplasma are pleomorphic and stain Gram-negative because they _______________
answer
lack cell walls
question
Under what conditions does infection with Mycobacterium leprae develop into tuberculoid leprosy?
answer
When the immune system develops a vigorous cell-mediated response
question
The soil bacterium Nocardia asteroides can establish opportunistic infections of the ___________________
answer
skin, lungs, and CNS
question
Untreated streptococcal pharyngitis may progress to _________________
answer
scarlet fever or rheumatic fever
question
A sample of fluid from the lungs contains microbes that grow in filaments or clumps. The cells stain poorly in the Gram stain and are a pink-red when acid-fast stained. The bacteria in the sample are ____________________
answer
Mycobacterium species
question
What clinical manifestation do Staphylococcus aureus and Staphylococcus epidermidis share?
answer
Enterotoxins
question
The pathogenicity of primary tuberculosis is due to the fact that the mycobacteria ____________________
answer
prevent fusion of lysosomes with phagosomes
question
What streptococci is associated with dental caries?
answer
Viridans streptococci
question
Streptococcus agalactiae is associated with what disease?
answer
Neonatal bacteremia, neonatal meningitis, and neonatal pneumonia
question
What staphylococcal virulence factors produce the signs and symptoms of scalded skin syndrome?
answer
Exfoliative toxin
question
Listeria virulence is directly related to its ability to ___________________________
answer
live within cells and thus avoid exposure to the immune system of its host
question
What is FALSE about diphtheria?
answer
It's growth on Loeffler's medium is used for absolute diagnosis of the bacterium
question
What is the most common disease caused by Propionibacterium?
answer
Acne
question
Enterococcus faecalis bacteria can be distinguished from other Gram-positive cocci because enterococci _________________________
answer
can grow in the presence of bile salts
question
What is FALSE regarding Streptococcus pyogenes?
answer
It produces protein A, which inhibits opsonization
question
The neurotoxins of Clostridium botulinum produce _____________ paralysis by preventing muscle contraction
answer
flaccid
question
The body limits the migration of Streptococcus _______________ by binding it to the active site of secretory IgA, which the bacteria overcome by secreting secretory IgA protease
answer
pneumoniae
question
The aerobic endospore-former ______________ is a strict pathogen of humans and animals
answer
bacillus anthracis
question
Successful treatment of diphtheria requires the administration of _____________
answer
antitoxin
question
In countries where tuberculosis is common, people are vaccinated with _____, which contains attenuated Mycobacterium bovis bacteria
answer
BCG
question
_________________ grow at temperatures up to 45 Celsius, at pH levels as high as 9.6, and in 6.5% NaCl, but they lack structural and chemical elements that make them virulent in the intestinal tract
answer
Enterococcus
question
Common sources of Listeria are undercooked meats and vegetables and unpasteurized _______
answer
milk
question
Bacterial food poisoning resulting from Clostridium ______________ contamination is characterized by water diarrhea accompanied by intestinal cramping but not fever, and it resolved in about a day
answer
perfringens
question
________ is resistant to numerous antimicrobial agents; therefore, vancomycin is usually used for these infections
answer
MRSA
question
When streptococcal infections involve the skin and surrounding lymph nodes, triggering pain and inflammation, the condition is known as ____________
answer
erysipelas
question
A "summer cold" that lasts for weeks is characterized by sore throat, mild fever, dry cough, and malaise may be ____________ pneumonia
answer
walking
question
In its role in the development of acne, ______________ typically grows in sebaceous glands of the skin
answer
Propionbacterium
question
The presence of mycolic acid in the cell walls of the opportunistic pathogen ___________ results in it Gram staining poorly
answer
Nocardia
question
Infection with Corynebacterium diphtheria leads to the formation of _____________ which can severely impair respiratory function
answer
pseudomembranes
question
The ability to produce ____________ enables Staphylococcus aureus to penetrate and spread through tissues
answer
hyaluronidase
question
T/F enterococci have the ability to secrete bacteriocins, which inhibit the growth of other bacteria
answer
True
question
T/F a person comes into the clinic with a wound that is severely inflamed, very painful, and turning black and "bubbly". The diagnosis is leprosy.
answer
False
question
T/F Streptococcus pyogenes commonly causes streptococcal toxic shock syndrome in otherwise healthy people
answer
False
question
T/F group A streptococci are considered more virulent if their cytoplasmic membrane contains M protein
answer
True
question
T/F adult food borne botulism can be prevented by thouroughly cooking food (minimum 80 Celsius for 20 minutes) before it is eaten.
answer
True
question
T/F Staphylococcus aureus can produce a toxin that dissolves the demosomes that hold the adjoining cytoplasmic membranes of cells together and causes the patient's skin cells to separate from each other.
answer
True
question
T/F staphylococcus aureus poisoning is long-lasting because ingested bacteria produce enterotoxins in the digestive system.
answer
False
question
T/F the respiratory infection known as "walking pneumonia" is caused by Mycoplasma pneumoniae
answer
True
question
T/F Mycobacterium tuberculosis is able to persist and be spread in aerosols due to its ability to produce endospores
answer
False
question
T/F in contrast to other mycobacteria, Mycobacterium avium-intracellular simultaneously affects almost every organ in the body.
answer
True