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HACEK the organism do
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Colonize the oropharynx Slow growing gram negative bacilli and coccobacilli Like CO2 Rare causes of bacterial endocarditis and peritonitis
NEED to Know
NEED to Know
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HACEK Organisms
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Haemophilus, Actinobacillus, Cardiobacterium, Eikenella, Kingella
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Haemophilus
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Main pathogens are Haemophilus influenzae and Haemophilus ducreyi Can be speciated based on growth requirements
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Haemophilus plate
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X factor = hemin released upon hemoglobin breakdown
V factor = NAD compound produced by some bacteria and yeast
*Sheep RBC's produce NADase but Horse and Rabbit RBC's do not and can be utilized to grow haemophilus
V factor = NAD compound produced by some bacteria and yeast
*Sheep RBC's produce NADase but Horse and Rabbit RBC's do not and can be utilized to grow haemophilus
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Haemophilus / H. influenzae
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//H. influenzae Requires X and V Causes pink eye, meningitis, respiratory infections and pneumoniae Gram negative coccobacilli "Satellite" growth around Staphylococcus aureus
In will not grow on sheep agar
NEED TO KNOW
In will not grow on sheep agar
NEED TO KNOW
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Haemophilus / H. ducreyi
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Sexually transmitted disease Causes "chancroid" Requires X factor Very Fastidious and needs additional supplements to grow
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Aggregatibacter
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Rare cause of endocarditis Often after invasive dental procedures
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Capnocytophaga
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Rare cause of periodontitis and bacteremia in immunocompromised hosts Thin GNR with tapered ends on gram stain
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Eikenella
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Smells like bleach
Pits the agar when it grows
Causes wound infections following human bites
Can cause septicemia after dental extractions Prefers Chocolate agar but will grow on blood
Need to Know
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Kingella
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Short GNCB Some pit the agar like Eikenella Can cause endocarditis in the compromised host Can grow on Thayer Martin Catalase negative and oxidase positive
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