question
Exotoxins
answer
Mainly Gram positive & Gram negative bacteria
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endotoxin
answer
Gram-negative bacteria
question
endotoxin
answer
Portion of outer (cell wall) membrane released upon cell death
question
exotoxins
answer
metabolic product secreted from living cell
question
exotoxins
answer
protein or short peptide
question
endotoxin
answer
lipid portion of lipopolysaccharide (lipid A) of outer (cell wall) membrane
question
exotoxins
answer
high toxicity
question
endotoxin
answer
low toxicity but may be fatal in high doses
question
Exotoxins
answer
typically unstable at temps above 60 degrees
question
endotoxin
answer
stable for up to 1 hour at autoclave temp 121 degrees C
question
exotoxins
answer
Effect on host variable depending on source; may be cytotoxin, neurotoxin, enterotoxin
question
endotoxin
answer
causes host to have fever, lethargy, malaise, shock, blood coagulation
question
exotoxins
answer
no fever produced
question
endotoxin
answer
fever produced
question
exotoxins
answer
Strong antigenicity; stimulates antitoxin (antibody) production
question
endotoxin
answer
weak antigenicity
question
exotoxins
answer
toxoid formation for immunization by treatment with heat or fomaldehyde
question
endotoxin
answer
toxoid formation for immunization is not feasible
question
exotoxins
answer
botulism, tetanus, gas gangrene, diphtheria, cholera, plague, staphylococcal food poisoning
question
endotoxin
answer
typhoid fever, tularemia, endotoxic shock, UTIs, meningococcal meningitis
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