question
Why is the production of a vaccine for the common cold so difficult?
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The common cold is caused by many different viruses from very different viral families.
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The majority of cases of pneumonia are caused by
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Streptococcus pneumoniae.
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A pneumonia caused by Gram-positive diplococci is known as
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pneumococcal pneumonia.
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Which of the following is an opportunistic infection?
answer
legionellosis
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Neutrophils are inhibited from gathering at the site of infection by Mycobacterium tuberculosis by what virulence factor of the pathogen?
answer
cord factor
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Which of the following statements is TRUE regarding tuberculosis?
answer
It remains viable in dried aerosol droplets for up to eight months.
question
Bordetella pertussis causes whooping cough by
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interfering with the activity of ciliated epithelial cells in the trachea.
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The DTaP vaccine protects against which of the following respiratory diseases?
answer
pertussis
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Even though mycoplasmas pass through filters that normally trap bacteria, they are known to be bacteria, not viruses, because they
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contain both DNA and RNA and divide by binary fission.
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Which of the following factors is primarily responsible for the ability of Mycobacterium tuberculosis to survive long periods of time in dried droplets of respiratory aerosols?
answer
the presence of mycolic acid in the cell wall
question
A nursing student develops a positive reaction to the tuberculin skin test. A history reveals possible exposure to patients with tuberculosis. A sputum sample is acid-fast negative. When asked for vaccination records, the student reports that childhood vaccination records were lost when the family emigrated from a Southeast Asian country. What is the best explanation for the test results?
answer
The student has been exposed to Mycobacterium tuberculosis or was vaccinated with BCG vaccine.
question
Which of the following diseases is NOT correctly matched with a diagnostic feature or test that distinguishes it?
answer
pertussis: pseudomembrane
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Which of the following diseases is NOT correctly matched with a pathogen that causes it?
answer
pertussis: Borrelia pertussis
question
A nursing student has been given a tuberculin test prior to doing his clinical practicum at a nursing home. After about 36 hours, he notices a hard, red swelling at the test site. Which of the following is NOT a possible conclusion from this result?
answer
He should not be allowed to work at the nursing home, because he has an active case of tuberculosis.
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Which of the following virulence factors is NOT correctly paired with its function?
answer
pneumolysin: stimulates endocytosis of bacteria
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What is most likely to occur in a patient infected with a mutant strain of Bordetella pertussis that lacks functional adhesins?
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The bacterium would be less likely to colonize the patient's lower respiratory system.
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Which of the following statements is TRUE regarding infection with Mycoplasma pneumoniae?
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The causative agent attaches to ciliated cells in the respiratory tract.
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Recent outbreaks of multidrug-resistant HAI are primarily caused by members of the genus (Bordetella/ Klebsiella/Mycobacteria), Gram-negative opportunists.
answer
Klebsiella
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A type of pneumonia in which the alveoli and bronchioles become filled with pus is (emphysema/empyema/pleurisy).
answer
empyema
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When macrophages carry Mycobacterium tuberculosis to sites such as the bone marrow and spleen it results in (disseminated/secondary/reactivated) tuberculosis.
answer
disseminated
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Inflammation of the pharynx with pus-filled abscesses and swollen tonsils is known as
answer
streptococcal pharyngitis ("strep throat").
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The designation "group A," used to help classify Streptococcus pyogenes, refers to this bacterium's
answer
Lancefield antigen.
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Which of the following allows group A streptococci to spread through tissues by breaking down blood clots?
answer
streptokinase
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Which of the following Streptococcus pyogenes virulence factors kills leukocytes and erythrocytes?
answer
streptolysins
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Pathogenic streptococci of the upper respiratory tract (such as Streptococcus pyogenes) are distinguished from non-pathogenic streptococci by
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beta hemolytic activity.
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Diphtheria toxin kills cells by interfering with which of the following processes?
answer
protein synthesis
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Which of the following statements is TRUE concerning diphtheria?
answer
The signs and symptoms of the disease are directly caused by a bacterial toxin.
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Which of the following is a common cause of otitis media?
answer
Streptococcus pneumoniae
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Which of the following causes the characteristic arrangement of Corynebacterium diphtheriae cells when viewed on a slide?
answer
snapping division
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A key diagnostic sign of diphtheria is the presence of the (pseudomembrane/pharyngitis/rash/tubercle).
answer
pseudomembrane
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Why are nearly all AIDS patients at risk of developing Pneumocystis pneumonia?
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Pneumocystis jiroveci is a common member of the respiratory microbiota in humans and opportunistic pathogen.
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Exposure to large accumulations of bird dropping may result in which of the following mycoses?
answer
histoplasmosis
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T/F Cold viruses are prevented from infecting most areas of the body because these areas are either too warm or too acidic.
answer
True
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The attachment protein for almost all rhinoviruses is (BCG/ICAM-1/IgA). (Be sure your answer is in uppercase letters.)
answer
ICAM-1
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Which of the following organisms causes primary atypical pneumonia?
answer
Mycoplasma pneumoniae
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The smallest free-living microbes are (mycobacteria/mycoplasmas/Chlamydophila).
answer
mycoplasmas
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Strains of Mycobacterium tuberculosis designated as (BCG/MDR/XDR) strains are resistant in vitro to three or more antitubercular drugs in addition to isoniazid and rifampin. (Be sure to use uppercase letters in your answer.)
answer
XDR
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Croup is often a result of infection with which of the following?
answer
respiratory syncytial virus
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Pathogenic streptococci in the upper respiratory tract are distinguishable from nonpathogenic streptococci because they completely lyse blood cells. This is called __________.
answer
beta-hemolysis
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Which of the following is NOT associated with fever production?
answer
colds
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Glycoprotein spikes on the exterior of some viruses, such as influenza virus, are used to __________.
answer
recognize and attach to host cell receptors
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Pleomorphic bacteria __________.
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vary in size or shape
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Some bacteria make an M protein that destabilizes complement C3b. What is the main effect of this protein on host defenses?
answer
interfere with recognition by phagocytes and lysis of bacterium
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An infected person who is asymptomatic is called a __________.
answer
carrier
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Which of the following is known as the secretory antibody and is found in mucus of the respiratory tract?
answer
IgA
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Which of the following drugs would be most useful against a fungal infection?
answer
amphotericin B
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The bacterium that causes diphtheria is Gram-positive and produces a toxin that is coded for by phage genes. Which is NOT a correct conclusion from this statement?
answer
The toxin is an endotoxin.
question
The tuberculin skin test described in this chapter depends on the activity of sensitized T cells and requires 24-72 hours to develop. This means that it is which of the following?
answer
type IV hypersensitivity
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Which of the following is NOT a structure of the nasal cavity?
answer
nose
question
Lactoferrin __________.
answer
sequesters iron, making this nutrient unavailable to microbes
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The lower respiratory system normally lacks microbes because of all of the following EXCEPT __________.
answer
defensins
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Rhinosinusitis is also known as __________.
answer
an inflammation of the nasal cavity and sinuses
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All mycoplasma organisms __________.
answer
lack a cell wall
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Viral infections do not respond to typical antibiotic treatment. Why not?
answer
Viral pathogens are not alive and therefore cannot be "killed" by antibiotics.
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A reemerging disease __________.
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is one that had been in decline in incidence but is increasing in the number of infections per year again
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An organism that attacks the alveolar membrane __________.
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is in the lower respiratory system
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To quickly and accurately diagnose which strain of the influenza virus a person has, a laboratory would perform __________.
answer
an ELISA to check for antigen specificity
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You go to the doctor's complaining of a sore throat. He prescribes a course of oral penicillin to treat the infection. Two days later, your throat feels much better. Which type of pathogen was most likely responsible for your sore throat?
answer
Streptococcus pyogenes
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T/F Any inflammation of the lungs in which the alveoli and bronchioles fill with fluid is called pleurisy.
answer
False
question
Which of the following is NOT true of RSV infection?
answer
It is spread primarily by respiratory droplets.
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T/F Vaccination is possible for some varieties of the common cold.
answer
True
question
Glycoprotein spikes on the exterior of some viruses, such as influenzavirus, are used to __________.
answer
recognize and attach to host cell receptors
question
All of the following can be used to treat mycoplasma infections EXCEPT __________.
answer
penicillin
question
Which of the following modes of transmission is LEAST likely to transmit the common cold?
answer
sneezing
question
Rodents are a significant means of transmission of which of the following pathogens?
answer
hantaviruses
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T/F The tuberculosis vaccine is not routinely used in the United States because it is NOT very effective.
answer
false
question
T/F A person can have strep throat more than once.
answer
true
question
T/F Pneumocystis pneumonia is caused by a fungus.
answer
true
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Which of the following does NOT contribute to the virulence of Mycobacterium tuberculosis?
answer
endotoxin
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T/F Once mycobacteria enter the body, they can NEVER be completely killed by the immune system.
answer
False
question
T/F Consumption was the term used to describe diphtheria in the early 1900s.
answer
False
question
Which of the following diseases can be caused by only certain strains of Streptococcus pyogenes?
answer
scarlet fever
question
All of the following are true statements concerning Legionella (Legionnaires' disease) EXCEPT that __________.
answer
it can produce serious extrapulmonary infections
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T/F Cold viruses can infect any area of the body, although they cause symptoms only when they reproduce in the upper respiratory tract.
answer
False
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answer
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