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pathogenicity
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refers to the ability of an organism to cause disease.
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hyaluronidase
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An enzyme secreted by certain bacteria that hydrolyzes hyaluronic acid and helps spread microorganisms from their initial site of infection.
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parenteral route
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A portal of entry for pathogens by deposition directly into tissues beneath the skin and mucous membranes.
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endotoxins
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Part of the outer portion of the cell wall (lipid A) of most gram-negative bacteria; released on destruction of the cell.
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virulence
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refers to the degree of pathology caused by the organism.
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adherence
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Attachment of a microbe or phagocyte to another's plasma membrane or other surface.
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toxigenicity
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The capacity of a microorganism to produce a toxin.
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toxin
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Any poisonous substance produced by a microorganism.
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invasins
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A surface protein produced by Salmonella typhimurium and Escherichia coli that rearranges nearby actin filaments in the cytoskeleton of a host cell.
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exotoxins
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A protein toxin released from living, mostly gram-positive bacterial cells.
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coagulase
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A bacterial enzyme that causes blood plasma to clot.
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antigenic variation
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Changes in surface antigens that occur in a microbial population.
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toxemia
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The presence of toxins in the blood.
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intoxication
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A condition resulting from the ingestion of a microbially produced toxin.
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collagenase
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An enzyme that hydrolyzes collagen.
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