question
Mycobacterium tuberculosis (M. tb.) morphology/gram stain
answer
Has a waxy coating and is related to gram pos bacteria
question
Mycobacterium tuberculosis is an acid fast bacteria what is the significance of this
answer
it does not react to a gram stain
question
Virulence factors
answer
toxic lipids & mycolic acid
resistant to phagocytosis (survives in macrophages)
resistant to phagocytosis (survives in macrophages)
question
Where does it grow in the human?
answer
Lungs
question
What damage occurs
answer
Tissue damage
question
What is a Ghon complex and how is it detected
answer
calcified lesion
X-ray detectale
X-ray detectale
question
Pulmonary means?
answer
lungs
question
disseminated or miliary tb.
answer
bacteria travel through blood stream and spread throughout the body
question
How to treat Multi drug resistant tb. (MDR T.B.)
answer
month long treatments
isoniazid
isoniazid
question
What does isoniazid do
answer
blocks formation of mycolic acid
question
Treating active TB
answer
treat with multiple drugs to prevent antibiotic resistance
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