Haemophilus influenza
Which of the following bacterial species can be prevented by vaccination?
A. Neisseria gonorrhoeae
B. Haemophilus influenza
C. Staphylococcus aureusus
D. Francisella tularensis
Plasmid-medicated DNA alterations
Which of the following represents a genetic base of resistance?
A. physical separation of bacteria from antibiotic
B. Bacteria that exist in a resting state
C. Plasmid-medicated DNA alterations
D. Bacteria surving as a protoplast
General reducing agent; inhibits DNA synthesis
What is the mechanism of action of metronidazole?
A. Proton pump inhibitor
B. Fungal sterol synthesis inhibitor
C. Mycolic acid synthesis inhibitor
D. General reducing agent; inhibits DNA synthesis
What is the mechanism of action of trimethoprim?
A. inhibit nucleic acid precursor synthesis
B. Alter cell membrane function
C. Inhibit protein synthesis
D. Inhibit mRNA synthesis
Which of the following bacterium is most commonly acquired through zoonotic transmission?
A. Francisella tularensis
B. Bacillus anthracis
C. Chlamydia trachomatis
D. Streptococcus pneumonia
In treating which of the of following bacterium would you anticipate the Jarisch-Herxheimer reaction?
A. Mycobacterium perae
B. Neisseria meningitidis
C. Treponema pallidum
D. Staphylococcus aureus
Which of the following antibiotics works by inhibiting RNA synthesis?
A. Rifampin
B. Doxycycline
C. Vancomycin
D. Cefriaxone
Bacteria produce siderophores to bind to which metal?
A. Calcium
B. Iron
C. Sodium
D. Magnesium
Which of the following bacteria would you expect to be able to produce an endotoxin?
A. Staphylococcus aureus
B. Escherichia coli
C. Clostridium tetani
D. Actinomyces israeli
A. They are Gram-positive cocci
B. They decrease the pathogenesis of a variety of hosts (nematodes)
C. They are intracellular within nematodes such as Wuchereria bancrofti
D. They are typically treated with penicillin G
Which of the following antibiotics inhibits mycolic acid synthesis, and is useful for treating Mycobacterium tuberculosis
A. Penicillin
B. Ethambutol
C. Isoniazid
D. Rifampin
Produces exotoxins such as ST and LT
Which of the following statements about Escherichia coli is accurate?
A. E. coli is a Gram-positive rod
B. E. coli is not normally a part of the human microbiome
C. Enterotoxigenic bacteria is typically treated with beta-lactam antibiotics
D. Produces exotoxins such as ST and LT
Which of the following drugs would you commonly administer with a beta lactam?
A. Cycloserine
B. Tazobactam
C. Tigecycline
D. Timethoprim
Peptidoglycan
The cell wall of bacteria is typically comprised of which material?
A. Hyaluronic acid
B. Peptidoglycan
C. Mycolic acid
D. Teichoic acid
Thin-walled, flexible spirochete; the causative agent of Lyme Disease
Which of the following statements most accurately reflects features of Borrelia burgdorferi?
A. Gram-positive cocci; causative agent of toxic shock syndrome
B. Gram-negative bacilli; can cause hemolytic uremia syndrome
C. Intracellular parasite; causative agent of Rocky Mountain Spotted Fever
D. Thin-walled, flexible spirochete; causative agent of Lyme Disease
Viruses
Prions
Which of the following microbes is considered non-living? Select all that apply.
A. Helminths
B. Viruses
C. Prions
D. Protozoa
Aerobes possess superoxide dismutase and catalase, which effectively neutralize ROS
Which of the following statements regarding aerobes is correct?
A. Aerobes possess superoxide dismutase and catalase, which effectively neutralize ROS
B. Aerobes grown when oxygen content is less than 20%; nitrogen may be used as the final electron acceptor
C. Oxygen is toxic to aerobes
D. Aerobes abuse abscesses
Neisseria meningitidis
Streptococcus pneumoniae
Select all that apply. Which bacterial species are most responsible for meningitis in infants? Select all that apply.
A. Neisseria meningitidis
B. Staphylococcus aureus
C. Mycobacterium tuberculosis
D. Streptococcus pneumoniae
Treponema pallidum : Syphilis
Which bacteria is correctly matched with the disease it causes?
A. Clostridium tetani: Anthrax
B. Treponema pallidum : Syphilis
C. Listeria monocytogenes : TUlaremia
D. Mycobacterium leprae : Rocky mountain spotted fever
Which of the following drugs works by inhibiting protein synthesis?
A. Ceftriaxone
B. Colistin
C. Ethambutol
D. Linezolid
Which of the following antibiotics would be inappropriate to treat mycoplasma pneumoniae?
A. Vancomycin
B. Eryhromycin
C. Doxycycline
D. Levofloxacin
Rifampin
Which of the following antibiotics is utilized as a first-line treatment against tuberculosis?
A. Azithromycin
B. Rifampin
C. Ceftiaxone
D. Ciprofloxacin
Drug inactivation
Altered drug target
Which of the following are mechanisms through which bacteria exhibit antibiotic resistance? Select all that apply.
A. Decreased drug efflux
B. Drug inactivation
C. Altered drug target
D. Increased drug permeability
Mouth
Colon
Where within the body would you normally expect to encounter microbes? Select all that apply.
A. Mouth
B. Liver
C. Colon
D. Kidneys
When Staphyloccoccus aureus becomes 'MRSA' it has acquired resistance to which class of antibiotics?
A. Fluoroquinolones
B. Polymyxins
C. Macrolides
D. Beta-lactams