Thus the drugs to treat these infections have to be numerous, so that they target the susceptibility of each bacterial pathogen. Thus, the advances in pharmacology have brought forward a new era of antibiotics with vast options to treat the infections that were once considered lethal in the history of mankind. Major disease epidemics in the history of the world, like the Black Death by plague in early 1900s that caused deaths of millions of people were brought under control successfully with the help of antibiotics (Levinson 2008). Endemic diseases like Tuberculosis, that have been a scourge for humanity for ages and were uncontrollable despite the use of innumerable drugs and therapies, have been found to be susceptible to different combinations of antibiotics. Worldwide measures are now being taken to eradicate such diseases from the face of the earth. Thus, single or in combination, antibiotics have opened the new doors to healthy life for the sick people who had no chances of survival. Antibiotics themselves are the products of microorganisms. The drug substance produced by one microorganism has adverse effects on certain other microorganisms and serves to kill them. This is how the antibiotics were produced initially. Due to their remarkable effects on wound healing and recovery from infections, soon they became famous with the names like ‘magic bullet’ and ‘wonder drug’ (Aminov 2010, Levinson 2008).
The origin of the use of antibiotics for treating the infections is as old as the infections themselves. Different communities in the past used living organisms to treat infections. In ancient times, different types of moulds were used by people to heal wounds and infections. Tetracycline antibiotics have the ability to get incorporated in the bones and accumulate in them.